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Advances in Differential Diagnosis and Management of Growth Hormone Deficiency in Children by Camille Hage; Hoong-Wei Gan; Anastasia Ibba; Giuseppa Patti; Mehul Dattani; Sandro Loche; Mohamad Maghnie; Roberto Salvatori is a Medicine article available to read on EtoBox.

What is Advances in Differential Diagnosis and Management of Growth Hormone Deficiency in Children about?

Growth hormone (GH) deficiency (GHD) in children is defined as impaired production of GH by the pituitary gland that results in growth failure. This disease might be congenital or acquired, and occurs in isolation or in the setting of multiple pituitary hormone deficiency. Isolated GHD has an estimated prevalence of 1 patient per 4000-10,000 live births and can be due to multiple causes, some of which are yet to be determined. Establishing the correct diagnosis remains key in children with short stature, as initiating treatment with recombinant human GH can help them attain their genetically determined adult height. During the past two decades, our understanding of the benefits of continuing GH therapy throughout the transition period from childhood to adulthood has increased. Improvements in transitional care will help alleviate the consequent physical and psychological problems that can arise from adult GHD, although the consequences of a lack of hormone replacement are less severe in adults than in children. In this Review, we discuss the differential diagnosis in children with GHD, including details of clinical presentation, neuroimaging and genetic testing. Furthermore, we hig

Who reads Advances in Differential Diagnosis and Management of Growth Hormone Deficiency in Children?

Author

Camille Hage; Hoong-Wei Gan; Anastasia Ibba; Giuseppa Patti; Mehul Dattani; Sandro Loche; Mohamad Maghnie; Roberto Salvatori

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)