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What is Understanding Hemolytic-Uremic Syndrome about?

Hemolytic-uremic syndrome (HUS) is primarily caused by damage to endothelial cells, leading to thrombotic microangiopathy and red blood cell fragmentation. It is classified into typical HUS, associated with Shiga-like toxin (Stx-HUS), and atypical HUS, which is non-Stx-associated, with the former having a better prognosis. Atypical HUS can be sporadic or familial, often resulting in severe outcomes, including end-stage renal disease and high mortality rates, particularly in familial cases linked to genetic

Author

madimadi11

Language

EN