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This document discusses control of normal cardiac contractility. It begins by describing how contraction results from the interaction of calcium ions with actin and myosin filaments in the cardiac sarcomere. The amount of calcium released from the sarcoplasmic reticulum determines contractility, and is proportional to the amount stored and the amount of trigger calcium that enters the cell during an action potential. Several processes influence calcium handling and contractility, including calcium sensitivi

Author

Dana Hamarsheh

Language

EN