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Developing an Antibiogram for Empiric Antibiotic Prescribing for Adult Non-spinal Orthopaedic Infections in a Developing World Setting by Ashley Arakkal; Chad M. Centner; Thomas Hilton; Marc Nortje; Michael Held; Stephen Roche; Adrian J. Brink; Marc Mendelson; Maritz Laubscher is a Medicine article available to read on EtoBox.
What is Developing an Antibiogram for Empiric Antibiotic Prescribing for Adult Non-spinal Orthopaedic Infections in a Developing World Setting about?
## Purpose Empiric antibiotic strategies in the treatment of fracture-related infections, chronic osteomyelitis, prosthetic joint infection, and septic arthritis should be based on local microbiological antibiograms. This study aims to describe the microbiology and review the antibiogram profiles of bacterial isolates from patients undergoing surgical treatment for non-spinal orthopaedic infections, to identify the most appropriate empiric antibiotic strategy. ## Methods A retrospective review was performed of all cases of non-spinal orthopaedic infections treated surgically from 1 January 2018 to 31 December 2018. The National Health Laboratory Service microbiology database was used to identify all intra-operative microbiological specimens obtained from orthopaedic patients, and data were correlated with the orthopaedic surgical database. Cases were divided into fracture-related infections, chronic osteomyelitis, prosthetic joint infection, and septic arthritis. Antibiotic susceptibility data were used to predict the efficacy of different empiric antibiotic regimens. ## Results A total of 107 cases were included in the study; 184 organisms were cultured. Overall, the most common o
Who reads Developing an Antibiogram for Empiric Antibiotic Prescribing for Adult Non-spinal Orthopaedic Infections in a Developing World Setting?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ashley Arakkal; Chad M. Centner; Thomas Hilton; Marc Nortje; Michael Held; Stephen Roche; Adrian J. Brink; Marc Mendelson; Maritz Laubscher
- Publisher
- Springer Paris
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)