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Validation of Prognostic Scores for Clinical Use in Patients with Alcoholic Hepatitis by Thomas Damgaard Sandahl; Peter Jepsen; Peter Ott; Hendrik Vilstrup is a Medicine article available to read on EtoBox.

What is Validation of Prognostic Scores for Clinical Use in Patients with Alcoholic Hepatitis about?

## Objective: In patients with alcoholic hepatitis, assessment of mortality risk is a key factor in the clinical management. within the last decade, several prognostic scores have emerged. we aimed to evaluate and compare the predictive performances of the glasgow alcoholic hepatitis score (gahs); the model of end-stage liver disease (meld); the meld-na; the lille model; and the age, bilirubin, international normalized ratio, and creatinine (abic) score in a population-based unselected cohort of patients with alcoholic hepatitis. ## Material and methods: We applied the scoring systems to all 274 patients hospitalized and diagnosed with alcoholic hepatitis (1999-2008) in a danish region of 1.1 million inhabitants. the ability of each score to predict mortality was evaluated using receiver operating characteristics curves, and the area under the receiver operating characteristics curves (aurocs) were used to compare the scores. ## Results: The 28-day mortality was 16%, 84-day 27%, and 180-day 40%. the models had similar predictive properties with auroc = 0.74-0.78 for 28-day mortality, 0.69-0.77 for 84-day mortality, and 0.65-0.75 for 180-day mortality. there were no statistically si

Who reads Validation of Prognostic Scores for Clinical Use in Patients with Alcoholic Hepatitis?

Author

Thomas Damgaard Sandahl; Peter Jepsen; Peter Ott; Hendrik Vilstrup

Publisher

Informa plc; Informa UK (Taylor & Francis); Taylor & Francis; Informa UK Limited (ISSN 0036-5521)

Published

2011

Language

EN

Field

Medicine (Health Sciences)