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What is Neonatal Pharmacokinetics Overview about?

This document summarizes key aspects of neonatal pharmacology and pharmacokinetics. It discusses how factors like gestational age, body composition, disease states, and organ maturation can impact drug absorption, distribution, metabolism and elimination in neonates. Specifically, it notes that preterm neonates have delayed gastric emptying and reduced gastric acid production, impacting oral drug absorption. It also explains that preterm neonates have higher body water content and different protein binding

Author

Rafael Flores Pinto

Language

EN