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Dietary Whey Protein Supplementation Increases Immunoglobulin G Production by Affecting Helper T Cell Populations after Antigen Exposure by Ha, Dong Jin (author);Kim, Jonggun (author);Kim, Saehun (author);Go, Gwang-Woong (author);Whang, Kwang-Youn (author) is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Dietary Whey Protein Supplementation Increases Immunoglobulin G Production by Affecting Helper T Cell Populations after Antigen Exposure about?
Whey protein is a by-product of cheese and casein manufacturing processes. It contains highly bioactive molecules, such as epidermal growth factor, colony-stimulating factor, transforming growth factor-α and -β, insulin-like growth factor, and fibroblast growth factor. Effects of whey protein on immune responses after antigen (hemagglutinin peptide) injection were evaluated in rats. Experimental diets were formulated based on NIH-31M and supplemented with 1% amino acids mixture (CON) or 1% whey protein concentrate (WPC) to generate isocaloric and isonitrogenous diets. Rats were fed the experimental diets for two weeks and then exposed to antigen two times (Days 0 and 14). Blood was collected on Days 0, 7, 14, and 21 for hematological analysis. The WPC group showed decreased IgA and cytotoxic T cells before the antigen injection (Day 0) but increased IgG, IL-2, and IL-4 after antigen injection due to increased B cells and T cells. Helper T cells were increased at Days 14 and 21, but cytotoxic T cells were not affected by WPC. WPC may activate adaptive immunity (IgG) against antigen by modulating helper T cells. Bioactive molecules might contribute to the immune-enhancing effects of
Who reads Dietary Whey Protein Supplementation Increases Immunoglobulin G Production by Affecting Helper T Cell Populations after Antigen Exposure?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Ha, Dong Jin (author);Kim, Jonggun (author);Kim, Saehun (author);Go, Gwang-Woong (author);Whang, Kwang-Youn (author)
- Publisher
- MDPI AG
- Published
- 2021
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)