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Can I read Bacterial Cellulose Adhesive Composites for Oral Cavity Applications on EtoBox?
Bacterial Cellulose Adhesive Composites for Oral Cavity Applications by Juhi Singh; Nigel C.S. Tan; Usha Rani Mahadevaswamy; Nattharee Chanchareonsook; Terry W.J. Steele; Sierin Lim is a Materials Science article available to read on EtoBox.
What is Bacterial Cellulose Adhesive Composites for Oral Cavity Applications about?
Topical approaches to oral diseases require frequent dosing due to limited retention time. A mucoadhesive drug delivery platform with extended soft tissue adhesion capability of up to 7 days is proposed for on-site management of oral wound. Bacterial cellulose (BC) and photoactivated carbene-based bioadhesives (PDz) are combined to yield flexible film platform for interfacing soft tissues in dynamic, wet environments. Structure-activity relationships evaluate UV dose and hydration state with respect to adhesive strength on soft tissue mimics. The bioadhesive composite has an adhesion strength ranging from 7 to 17 kPa and duration exceeding 48 h in wet conditions under sustained shear forces, while other mucoadhesives based on hydrophilic macromolecules exhibit adhesion strength of 0.5-5 kPa and last only a few hours. The work highlights the first evaluation of BC composites for mucoadhesive treatments in the buccal cavity.
Who reads Bacterial Cellulose Adhesive Composites for Oral Cavity Applications?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Juhi Singh; Nigel C.S. Tan; Usha Rani Mahadevaswamy; Nattharee Chanchareonsook; Terry W.J. Steele; Sierin Lim
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Materials Science (Physical Sciences)