Can I read 1058: An Interim Analysis of a Phase III Randomized Trial of Using FDG-PET in the Management of Cervical Cancer Patients With Positive Pelvic Node on MRI Image on EtoBox?

1058: An Interim Analysis of a Phase III Randomized Trial of Using FDG-PET in the Management of Cervical Cancer Patients With Positive Pelvic Node on MRI Image by J. Hong; C. Tsai; T. Chang; C. Lai; T. Yen; K. Ng; H. Chou; S. Ma; C. Wang is a Medicine article available to read on EtoBox.

What is 1058: An Interim Analysis of a Phase III Randomized Trial of Using FDG-PET in the Management of Cervical Cancer Patients With Positive Pelvic Node on MRI Image about?

both prior to therapy and at the time of brachytherapy are critical for target delineation, tandem loading and brachytherapy dose prescription. This study assessed temporal radiation-induced changes of these imaging parameters relevant for target delineation and dose prescription in image-based brachytherapy. Materials/Methods: Linear and volumetric measurements of uterus and tumor were performed in 90 MR studies of 30 cervical cancer patients. Each patient had three serial MRIs, pre-treatment, at 20-25 Gy, and at 45-50 Gy. Volume of tumor and normal uterus, length of the uterine canal and extent of tumor along the canal were measured and analyzed with respect to the three imaging time points. Results: All measured imaging parameters, except the normal uterus, showed progressive decrease in a highly variable pattern during radiation therapy. The uterine canal length decreased from a mean of 7.8 cm pre-therapy (range: 4.1-11.8 cm) to 7.1 cm (range: 4.2-10.2 cm) at 20-25 Gy, and to 5.8 cm (range: 3.0-9.1 cm) at 45-50 Gy. Regression of the linear tumor extent along the endometrial canal was not proportional and occurred more rapidly from 4.1 cm pre-therapy to 3.5 cm (range: 1.2-7.1 cm

Who reads 1058: An Interim Analysis of a Phase III Randomized Trial of Using FDG-PET in the Management of Cervical Cancer Patients With Positive Pelvic Node on MRI Image?

Author

J. Hong; C. Tsai; T. Chang; C. Lai; T. Yen; K. Ng; H. Chou; S. Ma; C. Wang

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2006

Language

EN

Field

Medicine (Health Sciences)