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Does Intensity-modulated Stereotactic Radiotherapy Achieve Superior Target Conformity than Conventional Stereotactic Radiotherapy in Different Intracranial Tumours? by S.D. Sharma; R. Jalali; R.D. Phurailatpam; T. Gupta is a Agricultural and Biological Sciences article available to read on EtoBox.

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Aims: To compare the dosimetric outcome of various conventional stereotactic radiotherapy (SRT) techniques with intensity-modulated stereotactic radiotherapy (IMSRT) in brain tumours of varying shape, size, location and proximity to organs at risk (OARs). Materials and methods: Fused computed tomography and magnetic resonance imaging datasets of four patients with different brain tumours previously treated with non-coplanar static conformal fields (SCF) were re-planned on the BrainScan treatment planning system using non-coplanar conformal arcs (CA), dynamic conformal arcs (DCA) and IMSRT with coplanar (IMSRT\_CP) or non-coplanar (IMSRT\_NCP) beam arrangement. Beam shaping and intensity modulation were carried out using a BrainLab micromultileaf collimator. The primary objective for each plan was to encompass R99% of the planning target volume (PTV) by O95% of the prescribed dose while minimising the dose to OARs. Results: The mean PTV coverage in SCF, CA, DCA, IMSRT\_NCP and IMSRT\_CP was 99.2, 99.5, 99.4, 99.2 and 99.2%, respectively. The highest dose within the target was !107% of the prescribed dose in all plans. Conformity was found to vary depending on the shape and location

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Author

S.D. Sharma; R. Jalali; R.D. Phurailatpam; T. Gupta

Publisher

Elsevier Science; Springer; Elsevier ; Springer-Verlag; W. B. Saunders Co., Ltd.; Springer Verlag; Elsevier BV; Springer Science and Business Media LLC (ISSN 1433-2981)

Published

2009

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)