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Early lens development in the zebrafish: A three‐dimensional time‐lapse analysis by Teri M.S. Greiling; John I. Clark is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Early lens development in the zebrafish: A three‐dimensional time‐lapse analysis about?
## Abstract In vivo, high‐resolution, time‐lapse imaging characterized lens development in the zebrafish from 16 to 96 hr postfertilization (hpf). In zebrafish, the lens placode appeared in the head ectoderm, similar to mammals. Delamination of the surface ectoderm resulted in the formation of the lens mass, which progressed to a solid sphere of cells separating from the developing cornea at approximately 24 hpf. A lens vesicle was not observed and apoptosis was not a major factor in separation of the lens from the future cornea. Differentiation of primary fibers began in the lens mass followed by formation of the anterior epithelium after delamination was complete. Secondary fibers differentiated from elongating epithelial cells near the posterior pole. Quantification characterized three stages of lens growth. The study confirmed the advantages of live‐cell imaging for three‐dimensional quantitative structural characterization of the mechanism(s) responsible for cell differentiation in formation of a transparent, symmetric, and refractile lens. Developmental Dynamics 238:2254–2265, 2009. © 2009 Wiley‐Liss, Inc.
Who reads Early lens development in the zebrafish: A three‐dimensional time‐lapse analysis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Teri M.S. Greiling; John I. Clark
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1058-8388)
- Published
- 2009
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)