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Protein fouling in microfiltration: deposition mechanism as a function of pressure for different pH by C Velasco; M Ouammou; J.I Calvo; A Hernández is a Chemistry article available to read on EtoBox.

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The influence of applied pressure on the fouling mechanism during bovine serum albumin (BSA) dead-end microfiltration (MF) has been investigated for a polyethersulfone acidic negatively charged membrane (ICE-450) from Pall Co. BSA solutions at pH values of 4, 5 (almost equal to the protein isoelectric point, IEP), and 6 were microfiltered through the membrane at different applied transmembrane pressures. Results have been analyzed in terms of the usual blocking filtration laws and a substantial change in the fouling mechanism was observed as the pressure was increased, this change can be related to the specific membrane-protein and protein-protein interactions.

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Author

C Velasco; M Ouammou; J.I Calvo; A Hernández

Publisher

Elsevier Science; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 0021-9797)

Published

2003

Language

EN

Field

Chemistry (Physical Sciences)