Can I read The role of flagella in Clostridium difficile pathogenicity on EtoBox?

The role of flagella in Clostridium difficile pathogenicity by Emma Stevenson; Nigel P. Minton; Sarah A. Kuehne is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is The role of flagella in Clostridium difficile pathogenicity about?

Clostridium difficile is widely publicised as a problem in the health-care system. Disruption of the normal gut microbiota by antibiotic therapy allows C. difficile to colonise the colon. On colonisation, C. difficile produces two toxins that lead to disease, with symptoms ranging from mild-to-severe diarrhoea, to fulminant and often fatal pseudomembranous colitis (PMC). How C. difficile establishes initial colonisation of the host is an area of active investigation. Recently there has been increased research into the role of C. difficile flagella in colonisation and adherence. Novel research has also elucidated a more complex role of flagella in C. difficile virulence pertaining to the regulation of toxin gene expression. This review focuses on new insights into the specific role of C. difficile flagella in colonisation and toxin gene expression.

Who reads The role of flagella in Clostridium difficile pathogenicity?

Author

Emma Stevenson; Nigel P. Minton; Sarah A. Kuehne

Publisher

Elsevier BV

Published

2015

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)