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The study investigates the inhibitory effects of epicatechin gallate (ECG) on the enzymes α-amylase and α-glucosidase, which are crucial for carbohydrate digestion and linked to postprandial hyperglycemia. ECG demonstrated strong inhibitory efficiency with IC50 values of 45.30 μg/mL for α-amylase and 4.03 μg/mL for α-glucosidase, forming enzyme complexes that alter enzyme conformation. Additionally, ECG showed antagonistic effects when combined with acarbose for α-amylase inhibition, while exhibiting additi
- Author
- yuliasrirm
- Language
- EN