Opening book details…
Can I read Pulmonary Function Changes in Older Adults with and Without Metabolic Syndrome on EtoBox?
Pulmonary Function Changes in Older Adults with and Without Metabolic Syndrome by Brandao-Rangel, Maysa Alves Rodrigues (author);Moraes-Ferreira, Renilson (author);Oliveira-Junior, Manoel Carneiro (author);Santos-Dias, Alana (author);Bachi, André Luis Lacerda (author);Gabriela-Pereira, Giovana (author);de Oliveira Freitas, Simone (author);Araújo-Rosa, Amanda Cristina (author);Oliveira, Luis Vicente Franco (author);Frison, Claudio Ricardo (author);do Prado, Wagner Luiz (author);Raju, Raghavan Pillai (author);Balagopal, P Babu (author);Vieira, Rodolfo P (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Pulmonary Function Changes in Older Adults with and Without Metabolic Syndrome about?
## Abstract The low-grade inflammation associated with metabolic syndrome (MS) triggers functional and structural alterations in several organs. Whereas lung function impairment is well reported for older adult population, the effect of MS on functional and immunological responses in the lungs remains unclear. In this cross-sectional study we determined whether MS alters pulmonary function, and immunological responses in older adults with MS. The study sample consisted of older adults with MS (68 ± 3 years old; n = 77) and without MS (67 ± 3 years old; n = 77). Impulse oscillometry was used to evaluate airway and tissue resistance, and reactance. Biomarkers of inflammation and fibrosis were assessed in the blood and in breath condensate. The total resistance of the respiratory system (R5Hz; p < 0.009), and the resistance of the proximal (R20Hz; p < 0.001) and distal (R5Hz–R20Hz; p < 0.004) airways were higher in MS individuals compared to those without MS. Pro-inflammatory (leptin, IL-1beta, IL-8, p < 0.001; TNF-alpha, p < 0.04) and anti-inflammatory cytokines (adiponectin, IL-1ra, IL-10, p < 0.001), anti-fibrotic (relaxin 1, relaxin 3, Klotho, p < 0.001) and pro-fibrotic (VEGF, p
Who reads Pulmonary Function Changes in Older Adults with and Without Metabolic Syndrome?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Brandao-Rangel, Maysa Alves Rodrigues (author);Moraes-Ferreira, Renilson (author);Oliveira-Junior, Manoel Carneiro (author);Santos-Dias, Alana (author);Bachi, André Luis Lacerda (author);Gabriela-Pereira, Giovana (author);de Oliveira Freitas, Simone (author);Araújo-Rosa, Amanda Cristina (author);Oliveira, Luis Vicente Franco (author);Frison, Claudio Ricardo (author);do Prado, Wagner Luiz (author);Raju, Raghavan Pillai (author);Balagopal, P Babu (author);Vieira, Rodolfo P (author)
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)