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CK2 by Inder Kumar is a document available to read on EtoBox.
The study investigates the role of casein kinase 2 (CK2) in vaccinia virus (VACV) infection, revealing that CK2 is essential for VACV dissemination and actin tail formation. Inhibition of CK2 using TBB or RNA interference resulted in impaired actin tail formation and reduced cell-to-cell spread of the virus, although CK2 was not necessary for cell-associated enveloped virus formation. The findings suggest that CK2 may enhance the recruitment of Src to CEVs through A36 phosphorylation, facilitating efficient
- Author
- Inder Kumar
- Language
- EN