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Can I read Human and Great Ape Red Blood Cells Differ in Plasmalogen Levels and Composition on EtoBox?
Human and Great Ape Red Blood Cells Differ in Plasmalogen Levels and Composition by Ann B Moser; Steven J Steinberg; Paul A Watkins; Hugo W Moser; Krishna Ramaswamy; Kimberly D Siegmund; D Rick Lee; John J Ely; Oliver A Ryder; Joseph G Hacia is a Medicine article available to read on EtoBox.
What is Human and Great Ape Red Blood Cells Differ in Plasmalogen Levels and Composition about?
## Background Plasmalogens are ether phospholipids required for normal mammalian developmental, physiological, and cognitive functions. They have been proposed to act as membrane antioxidants and reservoirs of polyunsaturated fatty acids as well as influence intracellular signaling and membrane dynamics. Plasmalogens are particularly enriched in cells and tissues of the human nervous, immune, and cardiovascular systems. Humans with severely reduced plasmalogen levels have reduced life spans, abnormal neurological development, skeletal dysplasia, impaired respiration, and cataracts. Plasmalogen deficiency is also found in the brain tissue of individuals with Alzheimer disease. ## Results In a human and great ape cohort, we measured the red blood cell (RBC) levels of the most abundant types of plasmalogens. Total RBC plasmalogen levels were lower in humans than bonobos, chimpanzees, and gorillas, but higher than orangutans. There were especially pronounced cross-species differences in the levels of plasmalogens with a C16:0 moiety at the __sn__-1 position. Humans on Western or vegan diets had comparable total RBC plasmalogen levels, but the latter group showed moderately higher level
Who reads Human and Great Ape Red Blood Cells Differ in Plasmalogen Levels and Composition?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ann B Moser; Steven J Steinberg; Paul A Watkins; Hugo W Moser; Krishna Ramaswamy; Kimberly D Siegmund; D Rick Lee; John J Ely; Oliver A Ryder; Joseph G Hacia
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2002-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1476-511X)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)