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Long-term Survival After Endoscopic Resection For Gastric Cancer: Real-world Evidence From a Multicenter Prospective Cohort by Suzuki, Haruhisa (author);Ono, Hiroyuki (author);Hirasawa, Toshiaki (author);Takeuchi, Yoji (author);Ishido, Kenji (author);Hoteya, Shu (author);Yano, Tomonori (author);Tanaka, Shinji (author);Toya, Yosuke (author);Nakagawa, Masahiro (author);Toyonaga, Takashi (author);Takemura, Kenichi (author);Hirasawa, Kingo (author);Matsuda, Mitsuru (author);Yamamoto, Hironori (author);Tsuji, Yosuke (author);Hashimoto, Satoru (author);Yuki, Maeda (author);Oyama, Tsuneo (author);Takenaka, Ryuta (author);Yamamoto, Yoshinobu (author);Naito, Yuji (author);Yamamoto, Katsumi (author);Kobayashi, Nozomu (author);Kawahara, Yoshiro (author);Hirano, Masaaki (author);Koizumi, Shigeto (author);Hori, Shinichiro (author);Tajika, Masahiro (author);Hikichi, Takuto (author);Yao, Kenshi (author);Yokoi, Chizu (author);Ohnita, Ken (author);Hisanaga, Yasuhiro (author);Sumiyoshi, Tetsuya (author);Kitamura, Shinji (author);Tanaka, Hisao (author);Shimoda, Ryo (author);Shimazu, Taichi (author);Takizawa, Kohei (author);Tanabe, Satoshi (author);Kondo, Hitoshi (author);Iishi, Hiroyasu (author);Ninomiya, Motoki (author);Oda, Ichiro (author);Mashimo, Yumi (author);Ishigooka, Masahiro (author);Fukase, Kazutoshi (author);Mizuguchi, Yasuhiko (author) is a Medicine article available to read on EtoBox.

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## Background & aims: We aimed to clarify the long-term outcomes of endoscopic resection (er) for early gastric cancers (egcs) based on pathological curability in a multicenter prospective cohort study. ## Methods: We analyzed the long-term outcomes of 9054 patients with 10,021 egcs undergoing er between july 2010 and june 2012. primary endpoint was the 5-year overall survival (os). the hazard ratio for all-cause mortality was calculated using the cox proportional hazards model. we also compared the 5-year os with the expected one calculated for the surgically resected patients with egc. if the lower limit of the 95% confidence interval (ci) of the 5-year os exceeded the expected 5-year os minus a margin of 5% (threshold 5-year os), er was considered to be effective. pathological curability was categorized into en bloc resection, negative margins, and negative lymphovascular invasion: differentiated-type, pt1a, ulcer negative, ≤2 cm (category a1); differentiated-type, pt1a, ulcer negative, >2 cm or ulcer positive, ≤3 cm (category a2); undifferentiated-type, pt1a, ulcer negative, ≤2 cm (category a3); differentiated-type, pt1b (sm1), ≤3 cm (category b); or noncurative resections (cat

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Author

Suzuki, Haruhisa (author);Ono, Hiroyuki (author);Hirasawa, Toshiaki (author);Takeuchi, Yoji (author);Ishido, Kenji (author);Hoteya, Shu (author);Yano, Tomonori (author);Tanaka, Shinji (author);Toya, Yosuke (author);Nakagawa, Masahiro (author);Toyonaga, Takashi (author);Takemura, Kenichi (author);Hirasawa, Kingo (author);Matsuda, Mitsuru (author);Yamamoto, Hironori (author);Tsuji, Yosuke (author);Hashimoto, Satoru (author);Yuki, Maeda (author);Oyama, Tsuneo (author);Takenaka, Ryuta (author);Yamamoto, Yoshinobu (author);Naito, Yuji (author);Yamamoto, Katsumi (author);Kobayashi, Nozomu (author);Kawahara, Yoshiro (author);Hirano, Masaaki (author);Koizumi, Shigeto (author);Hori, Shinichiro (author);Tajika, Masahiro (author);Hikichi, Takuto (author);Yao, Kenshi (author);Yokoi, Chizu (author);Ohnita, Ken (author);Hisanaga, Yasuhiro (author);Sumiyoshi, Tetsuya (author);Kitamura, Shinji (author);Tanaka, Hisao (author);Shimoda, Ryo (author);Shimazu, Taichi (author);Takizawa, Kohei (author);Tanabe, Satoshi (author);Kondo, Hitoshi (author);Iishi, Hiroyasu (author);Ninomiya, Motoki (author);Oda, Ichiro (author);Mashimo, Yumi (author);Ishigooka, Masahiro (author);Fukase, Kazutoshi (author);Mizuguchi, Yasuhiko (author)

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)