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Value of Dobutamine Stress Myocardial Contrast Perfusion Echocardiography in Patients with Advanced Liver Disease by Jeane M. Tsutsui; Sandeep Mukherjee; Abdou Elhendy; Feng Xie; Elizabeth R. Lyden; Edward O'Leary; Anna C. McGrain; Thomas R. Porter is a Medicine article available to read on EtoBox.
What is Value of Dobutamine Stress Myocardial Contrast Perfusion Echocardiography in Patients with Advanced Liver Disease about?
Although dobutamine stress echocardiography has been used for the preoperative evaluation of patients with advanced liver disease (ALD), no data exist regarding the value of myocardial perfusion imaging (MPI) with real-time myocardial contrast echocardiography (RTMCE) in this patient population. We sought to determine the value of MPI during dobutamine stress RTMCE for predicting prognosis in patients with ALD. We examined both wall motion and MPI in 230 patients with ALD who underwent dobutamine stress RTMCE using intravenous commercially available contrast agents (Optison, GE-Amersham, Princeton, NJ; or Definity, Bristol-Myers Squibb Medical Imaging, North Billerica, MA). The prognostic value of clinical variables, including the Model for End-Stage Liver Disease (MELD) score, and echocardiographic data were examined using a Cox Hazard model. The primary endpoint was mortality of all causes. Among the 85 patients who underwent orthotopic liver transplantation, 4 had abnormal MPI and 81 had normal perfusion. The hospital mortality rate was 50% (2/4) in patients with abnormal MPI and 2% (2/81) in patients with normal MPI (P ϭ 0.01). Among patients with abnormal MPI, 1 died from myoc
Who reads Value of Dobutamine Stress Myocardial Contrast Perfusion Echocardiography in Patients with Advanced Liver Disease?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Jeane M. Tsutsui; Sandeep Mukherjee; Abdou Elhendy; Feng Xie; Elizabeth R. Lyden; Edward O'Leary; Anna C. McGrain; Thomas R. Porter
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2006
- Language
- EN
- Field
- Medicine (Health Sciences)