About this Medicine article

Improving the Definition of Tumor Bed Boost With the Use of Surgical Clips and Image Registration in Breast Cancer Patients by Youlia M. Kirova; Pablo Castro Pena; Tarek Hijal; Nathalie Fournier-Bidoz; Fatima Laki; Brigitte Sigal-Zafrani; Rémi Dendale; Marc A. Bollet; Francois Campana; Alain Fourquet is a Medicine article available to read on EtoBox.

## Purpose: To evaluate the accuracy of a boost technique. ## Methods and materials: Twenty-two patients underwent tumorectomy with placement of two or more clips in the surgical cavity before breast remodeling. preoperative and postoperative computed tomography scans, with match-point registration, were performed on all patients. the relationship between the location of the gross tumor volume (gtv), defined on the preoperative scan, and clip clinical target volume (ctv) (clips with a 5-mm margin on the postoperative scan) was then studied, by use of commercial volume analysis software. ## Results: Of the patients, 4 had two clips, 2 had three clips, 8 had four clips, and 8 had five clips. the median gtv was 1.06 ml (range, 0.2-5.3 ml); clip ctv ranged from 2.4 to 21.5 ml. volumetric analysis showed that in 7 cases (32%), there was no intersection between the gtv and the clip ctv, with the following distribution: 4 patients with two clips, 1 patient with three clips, 1 patient with four clips, and 1 patient with five clips. the common contoured volume was defined as the percent ratio between the intersection of the gtv and clip ctv and the gtv. it was found to be significantly incr

Author

Youlia M. Kirova; Pablo Castro Pena; Tarek Hijal; Nathalie Fournier-Bidoz; Fatima Laki; Brigitte Sigal-Zafrani; Rémi Dendale; Marc A. Bollet; Francois Campana; Alain Fourquet

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2010

Language

EN

Field

Medicine (Health Sciences)