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Can I read Osteosclerosis, osteomalacia, and bone marrow aplasia: A combined late complication of thorotrast administration on EtoBox?
Osteosclerosis, osteomalacia, and bone marrow aplasia: A combined late complication of thorotrast administration by William A. Murphy; Paul A. Seligman; Thomas Tillack; John O. Eichling; Steven L. Teitelbaum; J. Heinrich Joist is a Medicine article available to read on EtoBox.
What is Osteosclerosis, osteomalacia, and bone marrow aplasia: A combined late complication of thorotrast administration about?
A 37-year-old female with thrombocytopenia since childhood developed diffuse osteosclerosis followed by bone marrow aplasia 23 years after Thorotrast administration. Tissue deposition of Thorotrast was documented by radiospectroscopy (liver, bone) and autoradiography (bone). Bone marrow failure in this patient was clinically ascribed to diffuse myelofibrosis, but at autopsy marrow fibrosis was only focal. An unsuspected bone mineralization defect was manifested by thick osteoid seams. It is suggested that osteosclerosis, osteomalacia, and bone marrow aplasia represent a combined expression of Thorotrast cytotoxicity.
Who reads Osteosclerosis, osteomalacia, and bone marrow aplasia: A combined late complication of thorotrast administration?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- William A. Murphy; Paul A. Seligman; Thomas Tillack; John O. Eichling; Steven L. Teitelbaum; J. Heinrich Joist
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0364-2348)
- Published
- 1979
- Language
- EN
- Field
- Medicine (Health Sciences)