Can I read Mitochondrial DNA Duplication and Deletion on EtoBox?

Mitochondrial DNA Duplication and Deletion by Haris kokkinis is a document available to read on EtoBox.

What is Mitochondrial DNA Duplication and Deletion about?

This study investigates a 12-year-old patient with mitochondrial encephalomyopathy and hypoparathyroidism, revealing complex mitochondrial DNA (mtDNA) rearrangements including deletions and duplications. The analysis showed that the muscle DNA contained three populations of mtDNA: wild type, deleted (65%), and duplicated (9%). These findings suggest that endocrinopathies other than diabetes can be associated with mtDNA duplications and support the hypothesis that deletions and duplications arise from the sa

Author

Haris kokkinis

Language

EN