Can I read Magnetic resonance imaging of prostatic cancer: Does detection vary between high and low gleason score tumors? on EtoBox?

Magnetic resonance imaging of prostatic cancer: Does detection vary between high and low gleason score tumors? by Ikonen, Saana; Krkkinen, Pivi; Kivisaari, Leena; Salo, Jaakko O.; Taari, Kimmo; Vehmas, Tapio; Tervahartiala, Pekka; Rannikko, Sakari is a Medicine article available to read on EtoBox.

What is Magnetic resonance imaging of prostatic cancer: Does detection vary between high and low gleason score tumors? about?

## BACKGROUND. Both Gleason score and prostate-specific antigen (PSA) concentration are prognostic factors for prostate cancer. We assessed our ability to localize cancer lesions based on Gleason scores and PSA values by endorectal coil magnetic resonance imaging (MRI). We also evaluated whether the size of the prostate affects tumor detectability. METHODS. We compared the findings of MRI and histopathological results of radical prostatectomy specimens from 63 patients; they were divided into four groups, based on Gleason score and also on serum PSA concentration. Furthermore, the possible effect of prostatectomy specimen weight on MRI interpretation was examined. RESULTS. A highly significant difference appeared in detection of cancer lesions based on their differentiation grade. No statistically significant difference existed between PSA groups in detection of tumors, but the large size of the prostate seemed to render image interpretation more difficult. CONCLUSIONS. Endorectal MRI detects poorly differentiated prostate cancer lesions more accurately than clinically insignificant tumors.

Who reads Magnetic resonance imaging of prostatic cancer: Does detection vary between high and low gleason score tumors??

Author

Ikonen, Saana; Krkkinen, Pivi; Kivisaari, Leena; Salo, Jaakko O.; Taari, Kimmo; Vehmas, Tapio; Tervahartiala, Pekka; Rannikko, Sakari

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0270-4137)

Published

2000

Language

EN

Field

Medicine (Health Sciences)