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What is DeepAMR Yang about?
The study presents DeepAMR, a deep learning model designed to predict co-occurring drug resistance in Mycobacterium tuberculosis using whole-genome sequencing data from a large cohort of TB patients. DeepAMR outperformed traditional models in predicting resistance to first-line anti-TB drugs, achieving high sensitivity and AUROC scores. Additionally, a clustering variant, DeepAMR_cluster, effectively captured lineage-related clusters in the latent space of the genomic data.
- Author
- jobs6862
- Language
- EN