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Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 Tesla by Xiaojuan Li; Benjamin C. Ma; Radu I. Bolbos; Robert Stahl; Jesus Lozano; Jin Zuo; Katrina Lin; Thomas M. Link; Marc Safran; Sharmila Majumdar is a Medicine article available to read on EtoBox.

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## Abstract ## Purpose To quantitatively assess bone marrow edema‐like lesion (BMEL) and the overlying cartilage in osteoarthritis (OA) or anterior cruciate ligament (ACL)‐injured knees using magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI). ## Materials and Methods Eight healthy controls and 30 patients with OA and other injuries who showed BMEL were scanned at 3.0T. A regression model was constructed to automatically calculate the volume of BMEL. Normalized T~1ρ~ z‐scores were calculated within BMEL‐overlying cartilage. Three‐dimensional (3D) MRSI was acquired in the BMEL and surrounding bone marrow. ## Results The mean T~1ρ~ z‐score was significantly higher in BMEL‐overlying cartilage than that in surrounding cartilage in the lateral tibia of patients with ACL tears (__P__ < 0.001). Significantly elevated water and unsaturated lipids, and decreased saturated lipids were observed in BMEL. The volume of elevated water correlated with the volume of BMEL. Water content was significantly higher within BMEL than that outside BMEL. The unsaturation index outside BMEL was significantly higher in patients with ACL tears than that in OA. ## Conclusion 3D MRSI and T~1ρ~ ma

Who reads Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 Tesla?

Author

Xiaojuan Li; Benjamin C. Ma; Radu I. Bolbos; Robert Stahl; Jesus Lozano; Jin Zuo; Katrina Lin; Thomas M. Link; Marc Safran; Sharmila Majumdar

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-1807)

Published

2008

Language

EN

Field

Medicine (Health Sciences)