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Abernethy Malformations: Evaluation and Management of Congenital Portosystemic Shunts by Shankar Rajeswaran; Andrew Johnston; Jared Green; Ahsun Riaz; Bartley Thornburg; Samdeep Mouli; Timothy Lautz; Caroline Lemoine; Riccardo Superina; James Donaldson is a Medicine article available to read on EtoBox.

What is Abernethy Malformations: Evaluation and Management of Congenital Portosystemic Shunts about?

## Purpose: To assess the utility of preoperative venography in evaluating and managing patients with congenital portosystemic shunts (cpsss). ## Materials and methods: A retrospective study was performed of 42 patients (62% female; median age, 4.1 years) diagnosed with a cpss from 2005 to 2018. preoperative venography (n = 39) and balloon occlusive pressure measurements (n = 33) within the mesenteric venous system guided treatment. primary outcome was serum ammonia levels at 1 month after shunt closure. management strategies included single (n = 12) or staged (n = 18) operative ligation, endovascular occlusion (n = 8), combined surgical and endovascular closure (n = 2), and observation (n = 2). ## Results: At 1 month, serum ammonia levels decreased from 82.5 ± 10.3 μmol/l to 38.4 ± 4.6 μmol/l (p < .001). no difference was observed in the decrease between patients treated surgically or endovascularly (p = .91). mean occluded to non-occluded pressure gradients were significantly lower for endovascular closure (5.3 ± 1.8 mmhg) than for surgical closure (12.3 ± 3.3 mmhg, p = .02). shunts were classified as extrahepatic in 29 patients and as intrahepatic in 13 patients; all shunts demo

Who reads Abernethy Malformations: Evaluation and Management of Congenital Portosystemic Shunts?

Author

Shankar Rajeswaran; Andrew Johnston; Jared Green; Ahsun Riaz; Bartley Thornburg; Samdeep Mouli; Timothy Lautz; Caroline Lemoine; Riccardo Superina; James Donaldson

Publisher

Elsevier Science; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 1051-0443)

Published

2020

Language

EN

Field

Medicine (Health Sciences)