Can I read Canine ACL reconstruction with an injectable hydroxyapatite/collagen paste for accelerated healing of tendon-bone interface on EtoBox?

Canine ACL reconstruction with an injectable hydroxyapatite/collagen paste for accelerated healing of tendon-bone interface by Qingsong Jiang; Liren Wang; Zhanhong Liu; Jinlei Su; Yajun Tang; Peijie Tan; Xiangdong Zhu; Kai Zhang; Xing Ma; Jia Jiang; Jinzhong Zhao; Hai Lin; Xingdong Zhang is a Engineering article available to read on EtoBox.

What is Canine ACL reconstruction with an injectable hydroxyapatite/collagen paste for accelerated healing of tendon-bone interface about?

Healing of an anterior cruciate ligament (ACL) autologous graft in a bone tunnel occurs through the formation of fibrovascular scar tissue, which is structurally and compositionally inferior to normal fibrocartilaginous insertion and thus may increase the reconstruction failure and the rate of failure recurrence. In this study, an injectable hydroxyapatite/type I collagen (HAp/Col I) paste was developed to construct a suitable local microenvironment to accelerate the healing of bone-tendon interface. Physicochemical characterization demonstrated that the HAp/Col I paste was injectable, uniform and stable. The __in vitro__ cell culture illustrated that the paste could promote MC3T3-E1 cells proliferation and osteogenic expression. The results of a canine ACL reconstruction study showed that the reconstructive ACL had similar texture and color as the native ACL. The average width of the tunnel, total bone volume, bone volume/tissue volume and trabecular number acquired from micro-CT analysis suggested that the healing of tendon-bone interface in experimental group was better than that in control group. The biomechanical test showed the maximal loads in experimental group achieved app

Who reads Canine ACL reconstruction with an injectable hydroxyapatite/collagen paste for accelerated healing of tendon-bone interface?

Author

Qingsong Jiang; Liren Wang; Zhanhong Liu; Jinlei Su; Yajun Tang; Peijie Tan; Xiangdong Zhu; Kai Zhang; Xing Ma; Jia Jiang; Jinzhong Zhao; Hai Lin; Xingdong Zhang

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Engineering (Physical Sciences)