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ESP, EORTC, and EURACAN Expert Opinion: practical recommendations for the pathological diagnosis and clinical management of intermediate melanocytic tumors and rare related melanoma variants by Arnaud de la Fouchardiere; Willeke Blokx; Léon C. van Kempen; Boštjan Luzar; Sophie Piperno-Neumann; Susana Puig; Llucia Alos; Eduardo Calonje; Daniela Massi; on behalf of the ESP Dermatopathology Working Group; EORTC Melanoma Group; EURACAN is a Medicine article available to read on EtoBox.
What is ESP, EORTC, and EURACAN Expert Opinion: practical recommendations for the pathological diagnosis and clinical management of intermediate melanocytic tumors and rare related melanoma variants about?
The recent WHO classification of skin tumors has underscored the importance of acknowledging intermediate grade melanocytic proliferations. A multistep acquisition of oncogenic events drives the progressive transformation of nevi into melanomas. The various pathways described are modulated by the initial oncogenic drivers that define the common, blue, and Spitz nevi groups. Intermediate lesions are most often the result of a clonal evolution within such nevi. Based on this established classification, we have suggested for each pathway a practical diagnostic approach, benefiting from the recently developed molecular tools, both in the setting of general pathology labs and expert centers. Moreover, recommendations regarding the re-excision and clinical follow-up are given to support decision-making in multidisciplinary tumor boards.
Who reads ESP, EORTC, and EURACAN Expert Opinion: practical recommendations for the pathological diagnosis and clinical management of intermediate melanocytic tumors and rare related melanoma variants?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Arnaud de la Fouchardiere; Willeke Blokx; Léon C. van Kempen; Boštjan Luzar; Sophie Piperno-Neumann; Susana Puig; Llucia Alos; Eduardo Calonje; Daniela Massi; on behalf of the ESP Dermatopathology Working Group; EORTC Melanoma Group; EURACAN
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)