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The Comparative Anatomy of the Pig Middle Ear Cavity: a Model for Middle Ear Inflammation in the Human? by J. P. PRACY; A. WHITE; Y. MUSTAFA; D. SMITH; M. E. PERRY is a Earth and Planetary Sciences article available to read on EtoBox.

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This study was undertaken to develop a functional model of otitis media with effusion (OME) in the pig (__Sus scrofa__), with the purpose of investigating the origin of lymphocytes populating the middle ear during the course of an inflammatory process. The relevance of the model to the human condition of OME is to a large extent dependent on the anatomical and physiological similarities between the middle ear cavity and the pharyngeal lymphoid tissue of the pig and man. Anatomical specimens were collected from 7 young Large White pigs to determine the gross anatomy of the middle ear cavity and the histological characteristics of the middle ear mucosa. It was found that the anatomy of the 3 parts of the middle ear cavity in man and in the pig is broadly similar, although some minor differences were observed. The porcine eustachian tube was seen to be cartilaginous throughout its length in contrast to the part osseous, part cartilaginous structure found in man; the porcine ossicles were slightly different in shape to those of man and the air cell system was situated inferior to the tympanic cavity in the pig as opposed to posteriorly in man. This paper describes the structure and mor

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Author

J. P. PRACY; A. WHITE; Y. MUSTAFA; D. SMITH; M. E. PERRY

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0021-8782)

Published

1998

Language

EN

Field

Earth and Planetary Sciences (Physical Sciences)