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What is Treatment Strategies for Plasmablastic Lymphoma about?

Plasmablastic lymphoma (PBL) is a rare and aggressive type of non-Hodgkin lymphoma with a poor prognosis. It is strongly associated with HIV infection or other immunosuppressed states. PBL cells resemble plasmablasts and typically express markers of plasma cells but lack B-cell markers. EBV infection and MYC dysregulation play important roles in the pathogenesis of PBL. Current therapies are generally inadequate, though intensive chemotherapy regimens and hematopoietic stem cell transplantation show promise

Author

vladimirkulf2142

Language

EN