About this document
UEG Journal - 2026 - Sirtl - NLRP3 Inflammasome Activation Induced Acute Papillitis As A Trigger of Acute Pancreatitis A by roger adalberto caruajulca arana is a document available to read on EtoBox.
This study investigates the mechanism by which microlithiasis induces acute pancreatitis, focusing on NLRP3 inflammasome activation. Results show increased inflammatory markers in human biopsies and suggest that cholesterol and bilirubinate crystals can activate NLRP3 in macrophages. The findings propose a novel pathway where biliary microlithiasis causes local inflammation at the papilla without obstructing pancreatic outflow, contributing to acute pancreatitis development.
- Author
- roger adalberto caruajulca arana
- Language
- EN