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Serial block-face scanning electron microscopy (SBEM) allows for volumetric reconstruction of neural tissue at electron microscopic resolution, enabling mapping of neural circuitry. Dr. Kevin Briggman used SBEM to map the connections between starburst amacrine cells and bipolar ganglion cells in mouse retina, elucidating the cellular circuit between these cells and helping understand wiring specificity. Briggman reconstructed neural processes based on morphology but synapses were initially invisible; staini
- Author
- Doby Mezepekenia
- Language
- EN