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Class I drugs like procainamide inhibit sodium channels and slow Phase 0 depolarization, decreasing automaticity and contractility. Common side effects include hypotension, bronchospasm, and heart block. Class II drugs like propranolol are beta-adrenergic receptor antagonists that decrease heart rate and contractility. They are used for tachyarrhythmias caused by increased sympathetic activity. Class III drugs like dofetilide are potassium channel inhibitors that prolong the action potential duration and
- Author
- Tesnikola
- Language
- EN