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Efficacy of Beta Oscillations in Identifying Effective Contact Point While Programming in Advanced Parkinson’s Disease Patients by Manish Baldia; Paresh K. Doshi; Bharati Karkera; Sonali Vasnik; Pettarusp M. Wadia is a Medicine article available to read on EtoBox.
What is Efficacy of Beta Oscillations in Identifying Effective Contact Point While Programming in Advanced Parkinson’s Disease Patients about?
Aim and Objectives: To measure local field potential (LFP) while programming with Medtronic Percept PC device in Advanced Parkinson Disease patients and correlate the derived contact point with the effective contact point Methods: Patients with advanced Parkinson disease implanted with the Medtronic Percept PC DBS device were selected. Age, duration of disease, OFF period rigidity, bradykinesia and LFP's of different contact points were documented. Contact point with the highest beta range frequency was identified and cross checked with the contact point yielding the best clinical response (Fig 1 ## ). Results: There were 7 patients (14 electrodes) included in the study. Mean duration of their Parkinson's disease was 10.7 years (7 -14 years). Beta band LFP's obtained were in the range of 11.72 to 27.34 hertz. Out of 14 electrodes, three electrodes (21%) did not show Beta band due to artefact (2) and unknown cause (1). Among the 11 electrodes which showed beta band, 10 (90.9%) correlated with the final effective contact point (Table 1). Conclusion: Adaptive stimulation has gained significance with the technology of measuring the neuronal activity in brain. Local field potential (LFP
Who reads Efficacy of Beta Oscillations in Identifying Effective Contact Point While Programming in Advanced Parkinson’s Disease Patients?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Manish Baldia; Paresh K. Doshi; Bharati Karkera; Sonali Vasnik; Pettarusp M. Wadia
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)