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Dmrt1 Expression in Response to Estrogen Treatment in a Reptile with Temperature-dependent Sex Determination by Chris Murdock; Thane Wibbels is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract Dmrt1 has been implicated as an important factor in sex determination in all classes of vertebrates, including reptiles with temperature‐dependent sex determination (TSD). Specifically, early embryonic expression of Dmrt1 appears to be an integral part of normal testicular development in vertebrates. Recently, a number of TSD studies have placed Dmrt1 expression at the top of a short list of putative temperature‐sensitive events for TSD. Dmrt1 expression has been shown to be up‐regulated at male‐producing temperatures during the thermosensitive period (TSP) of several TSD reptile species. An interesting finding in Dmrt1 studies of fish and amphibians has been that in species where exogenous steroids can stimulate sex reversal, Dmrt1 expression can also be manipulated by these steroid treatments. In the current study, we examine the effects of exogenous 17β‐estradiol treatment on Dmrt1 expression at male‐producing temperature (26°C) in a reptile with TSD, the red‐eared slider turtle, __Trachemys scripta__. Previous studies have demonstrated that exogenous estrogens can stimulate sex reversal (at male‐producing temperatures) in this species of turtle. In the current study

Who reads Dmrt1 Expression in Response to Estrogen Treatment in a Reptile with Temperature-dependent Sex Determination?

Author

Chris Murdock; Thane Wibbels

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 1552-5007)

Published

2006

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)