Opening book details…
Can I read Hypersensitivity reactions to anticancer chemotherapy and monoclonal antibodies: Safety and efficacy of desensitization on EtoBox?
Hypersensitivity reactions to anticancer chemotherapy and monoclonal antibodies: Safety and efficacy of desensitization by Rosalaura V Villarreal-González; Sandra González-Díaz; Oscar Vidal-Gutiérrez; Carlos de la Cruz-de la Cruz; Diana C Pérez-Ibave; María L Garza-Rodríguez is a Medicine article available to read on EtoBox.
What is Hypersensitivity reactions to anticancer chemotherapy and monoclonal antibodies: Safety and efficacy of desensitization about?
## Background Hypersensitivity reactions to anticancer chemotherapy and monoclonal antibodies may lead to discontinuation of first-line treatment options. Identification of these reactions can provide specific diagnosis and treatment by rapid drug desensitizations. ## Objective To determine the hypersensitivity reactions involved in anticancer chemotherapy and monoclonal antibodies, and the safety and efficacy of rapid drug desensitization. ## Methods We conducted an observational study of hypersensitivity reaction presented after the administration of anticancer chemotherapy and monoclonal antibodies in Mexico. We documented the symptoms of initial reaction and their severity, and the results of skin tests. We also report our experience of the administration of 12-step (mild-moderate reactions) and 16-step (severe reactions) desensitization protocols in these patients. ## Results Overall, 93 patients received 336 rapid drug desensitization; 105 to taxanes, 115 to platinum drugs, 101 to monoclonal antibodies, and 15 other anticancer chemotherapy. Hypersensitivity reaction to taxanes occurred in the first or second administration, platinum drugs after the sixth cycle, and rituximab
Who reads Hypersensitivity reactions to anticancer chemotherapy and monoclonal antibodies: Safety and efficacy of desensitization?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Rosalaura V Villarreal-González; Sandra González-Díaz; Oscar Vidal-Gutiérrez; Carlos de la Cruz-de la Cruz; Diana C Pérez-Ibave; María L Garza-Rodríguez
- Publisher
- SAGE Publications
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)