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This document discusses phagocytosis and its evaluation by flow cytometry. It describes the three stages of phagocytosis: opsonization, phagocytosis, and lysis. Pathogen destruction can occur through oxygen-dependent or -independent methods. Diseases caused by defects in phagocytosis include chronic granulomatous disease, which results from mutations impairing the production of reactive oxygen species needed to destroy pathogens. Flow cytometry allows indirect measurement of the respiratory burst and phagoc

Author

Devendra Gorle

Language

EN