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Randomized Clinical Trial of Donor-site Wound Dressings After Split-skin Grafting by F E Brölmann; A M Eskes; J C Goslings; F B Niessen; R de Bree; A C Vahl; E G Pierik; H Vermeulen; D T Ubbink is a Medicine article available to read on EtoBox.

What is Randomized Clinical Trial of Donor-site Wound Dressings After Split-skin Grafting about?

## Abstract ## Background The aim was to study which dressing material was best for healing donor-site wounds (DSWs) after split-skin grafting as there is wide variation in existing methods, ranging from classical gauze dressings to modern silicone dressings. ## Methods This 14-centre, six-armed randomized clinical trial (stratified by centre) compared six wound dressing materials in adult patients with DSWs larger than 10 cm2. Primary outcomes were time to complete re-epithelialization and pain scores measured on a visual analogue scale (VAS) over 4 weeks. Secondary outcomes included itching (VAS, over 4 weeks), adverse events and scarring after 12 weeks rated using the Patient and Observer Scar Assessment Scale (POSAS). ## Results Between October 2009 and December 2011, 289 patients were randomized (of whom 288 were analysed) to either alginate (45), film (49), gauze (50), hydrocolloid (49), hydrofibre (47) or silicone (48) dressings. Time to complete re-epithelialization using hydrocolloid dressings was 7 days shorter than when any other dressing was used (median 16 versus 23 days; P < 0·001). Overall pain scores were low, and slightly lower with use of film dressings (P = 0·038

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Author

F E Brölmann; A M Eskes; J C Goslings; F B Niessen; R de Bree; A C Vahl; E G Pierik; H Vermeulen; D T Ubbink

Publisher

Oxford University Press (OUP)

Published

2013

Language

EN

Field

Medicine (Health Sciences)