Can I read Hepatitis E Virus Infections: Epidemiology, Genetic Diversity, and Clinical Considerations on EtoBox?
Hepatitis E Virus Infections: Epidemiology, Genetic Diversity, and Clinical Considerations by Busara Songtanin; Adebayo J. Molehin; Kevin Brittan; Wuttiporn Manatsathit; Kenneth Nugent is a Medicine article available to read on EtoBox.
What is Hepatitis E Virus Infections: Epidemiology, Genetic Diversity, and Clinical Considerations about?
According to the World Health Organization, approximately 20 million people worldwide are infected annually with the hepatitis E virus (HEV). There are four main genotypes of HEV. Genotype 1 and genotype 2 are common in developing countries and are transmitted by contaminated water from a fecal–oral route. Genotype 3 and genotype 4 are common in developed countries and can lead to occasional transmission to humans via undercooked meat. Hepatitis E virus 1 and HEV3 can lead to fulminant hepatitis, and HEV3 can lead to chronic hepatitis and cirrhosis in immunocompromised patients. The majority of patients with HEV infection are asymptomatic and usually have spontaneous viral clearance without treatment. However, infection in immunocompromised individuals can lead to chronic HEV infection. Both acute and chronic HEV infections can have extrahepatic manifestations. No specific treatment is required for acute HEV infection, no treatment has been approved in chronic infection, and no HEV vaccine has been approved by the (United States) Food and Drug Administration. This review focuses on the molecular virology (HEV life cycle, genotypes, model systems, zoonosis), pathogenesis, clinical m
Who reads Hepatitis E Virus Infections: Epidemiology, Genetic Diversity, and Clinical Considerations?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Busara Songtanin; Adebayo J. Molehin; Kevin Brittan; Wuttiporn Manatsathit; Kenneth Nugent
- Publisher
- MDPI AG
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)