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Polyene macrolide antibiotics, primarily produced by Streptomyces spp., are effective antimycotics used to treat fungal infections, though their clinical use is limited due to toxicity and stability issues. Natamycin, a notable polyene antibiotic discovered in 1955, is produced through fermentation and has specific physical and chemical properties, including poor water solubility and a complex structure. The document also discusses the classification, production methods, and solubility characteristics of na

Author

raelsabri

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EN