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Predicting Trajectories of Behavioral Adjustment in Children Diagnosed with Acute Lymphoblastic Leukemia by Simone M. Sint Nicolaas; Peter M. Hoogerbrugge; Esther M. M. van den Bergh; José A. E. Custers; Sofia Gameiro; Reinoud J. B. J. Gemke; Chris M. Verhaak is a Medicine article available to read on EtoBox.
What is Predicting Trajectories of Behavioral Adjustment in Children Diagnosed with Acute Lymphoblastic Leukemia about?
## Purpose Previous research showed that children with cancer are at risk for developing behavioral adjustment problems after successful treatment; however, the course of adjustment remains unclear. This study focuses on adjustment trajectories of children during treatment for acute lymphoblastic leukemia (ALL) and aims to distinguish subgroups of patients showing different trajectories during active treatment, and to identify sociodemographic, medical, and psychosocial predictors of the distinct adjustment trajectories. ## Methods In a multicenter longitudinal study, 108 parents of a child (response rate 80 %) diagnosed with ALL were assessed during induction treatment (T0), after induction/consolidation treatment (T1), and after end of treatment (T2). Trajectories of child behavioral adjustment (Child Behavior Checklist; CBCL) were tested with latent class growth modeling (LCGM) analyses. ## Results For internalizing behavior, a three-trajectory model was found: a group that experienced no problems (60 %), a group that experienced only initial problems (30 %), and a group that experienced chronic problems (10 %). For externalizing behavior, a three-trajectory model was also found
Who reads Predicting Trajectories of Behavioral Adjustment in Children Diagnosed with Acute Lymphoblastic Leukemia?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Simone M. Sint Nicolaas; Peter M. Hoogerbrugge; Esther M. M. van den Bergh; José A. E. Custers; Sofia Gameiro; Reinoud J. B. J. Gemke; Chris M. Verhaak
- Publisher
- Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0941-4355)
- Published
- 2016
- Language
- EN
- Field
- Medicine (Health Sciences)