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Can I read The Multiomic Landscape of Meningiomas: a Review and Update on EtoBox?
The Multiomic Landscape of Meningiomas: a Review and Update by Justin Z. Wang; Farshad Nassiri; Alexander P. Landry; Vikas Patil; Jeff Liu; Kenneth Aldape; Andrew Gao; Gelareh Zadeh is a Medicine article available to read on EtoBox.
What is The Multiomic Landscape of Meningiomas: a Review and Update about?
Abstract Purpose Meningiomas are the most common primary brain tumor in adults. Traditionally they have been understudied compared to other central nervous system (CNS) tumors. However over the last decade, there has been renewed interest in uncovering the molecular topography of these tumors, with landmark studies identifying key driver alterations contributing to meningioma development and progression. Recent work from several independent research groups have integrated different genomic and epigenomic platforms to develop a molecular-based classification scheme for meningiomas that could supersede histopathological grading in terms of diagnostic accuracy, biological relevance, and outcome prediction, keeping pace with contemporary grading schemes for other CNS tumors including gliomas and medulloblastomas. Methods Here we summarize the studies that have uncovered key alterations in meningiomas which builds towards the discovery of consensus molecular groups in meningiomas by integrating these findings. These groups supersede WHO grade and other clinical factors in being able to accurately predict tumor biology and clinical outcomes following surgery. Results Despite differences
Who reads The Multiomic Landscape of Meningiomas: a Review and Update?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Justin Z. Wang; Farshad Nassiri; Alexander P. Landry; Vikas Patil; Jeff Liu; Kenneth Aldape; Andrew Gao; Gelareh Zadeh
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)