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Could a high cholesterol diet cause Alzheimer's disease in Western Society? [Hypothesis] by Robyn J. Holden is a Medicine article available to read on EtoBox.

What is Could a high cholesterol diet cause Alzheimer's disease in Western Society? [Hypothesis] about?

Epidemiological studies have found dierent prevalence rates for Alzheimer's disease in African-Asian, Saudi Arabian and European-American Societies. It is hypothesized that high cholesterol diet may account for the dierence in these prevalence rates given that elevated cholesterol can induce extracellular acidi®cation which, in turn, increase the expression of tumor necrosis factor-alpha. In this paper, a neuroimmunological explanation is advanced that outlines a possible causal pathway that leads from extracelular acidi®cation and elevated tumor necrosis factor-alpha to the three leading chacterisitics of Alzhemier's disease: senile plaques, neuro®brillary tangles and cognitive de®cits.

Who reads Could a high cholesterol diet cause Alzheimer's disease in Western Society? [Hypothesis]?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Robyn J. Holden
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0885-6222)
Published
1999
Language
EN
Field
Medicine (Health Sciences)

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