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Can I read Two selective novel triterpene glycosides from sea cucumber, Telenata Ananas: inhibitors of chemokine receptor-5 on EtoBox?
Two selective novel triterpene glycosides from sea cucumber, Telenata Ananas: inhibitors of chemokine receptor-5 by Vinod R. Hegde; T.-M. Chan; Haiyan Pu; Vincent P. Gullo; Mahesh G. Patel; Pradip Das; Nicole Wagner; P.S. Parameswaran; C.G. Naik is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Two selective novel triterpene glycosides from sea cucumber, Telenata Ananas: inhibitors of chemokine receptor-5 about?
The aqueous methanolic extract of a sea cucumber was found to contain two triterpene glycosides 1 and 2. The structures of 1 and 2 were established based on high-resolution NMR studies. Compounds 1 and 2 exhibited inhibitory activity (K(i)) of 30 and 5microM, respectively, in a chemokine receptor subtype 5 (CCR5) assay. Both compounds did not show any significant inhibition in a CXCR2 assay at 50microM, suggesting their selectivity for the CCR5 receptor.
Who reads Two selective novel triterpene glycosides from sea cucumber, Telenata Ananas: inhibitors of chemokine receptor-5?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Vinod R. Hegde; T.-M. Chan; Haiyan Pu; Vincent P. Gullo; Mahesh G. Patel; Pradip Das; Nicole Wagner; P.S. Parameswaran; C.G. Naik
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2002
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)