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Evaluation of Inflammatory Biomarkers Associated with Oxidative Stress and Histological Assessment of Low-level Laser Therapy in Experimental Myopathy by Natalia Servetto; David Cremonezzi; Juan C. Simes; Monica Moya; Fernando Soriano; Jose A. Palma; Vilma R. Campana is a Medicine article available to read on EtoBox.
What is Evaluation of Inflammatory Biomarkers Associated with Oxidative Stress and Histological Assessment of Low-level Laser Therapy in Experimental Myopathy about?
## Abstract The objective of the present work was to study the effect of helium–neon (He–Ne) and gallium–arsenide (Ga–As) laser upon inflammatory biomarkers associated with oxidative stress: fibrinogen, nitric oxide (NO), L‐citrulline, and superoxide dismutase (SOD). These were evaluated through histological assessment, in rats with experimental myopathy. __Materials and Methods:__ The groups studied were: (A) control, (B) injured, (C) injured and treated with He–Ne laser, (D) injured and treated with Ga–As laser, (E) irradiated with He–Ne; and (F) irradiated with Ga–As laser. Myopathy was induced by injecting 0.05 mg/rat/day of adrenaline in the left posterior limb muscle at the same point on 5 consecutive days, in groups B, C, and D. Low‐level laser therapy (LLLT) was applied with 9.5 J/cm^2^ daily for 7 consecutive days with each laser. The determination of the biomarkers was made by spectrophotometry. The muscles (5/8, single blinded) were stained with Gomori Trichrome and examined by optic microscopy. The quantitative variables were statistically analyzed by the Fisher's test and categorical data by the Axionvision 4.8 program. Pearson's chi‐squared test was applied, setting s
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- Author
- Natalia Servetto; David Cremonezzi; Juan C. Simes; Monica Moya; Fernando Soriano; Jose A. Palma; Vilma R. Campana
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0196-8092)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)