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Sjögren's syndrome associated with systemic lupus erythematosus: Clinical and laboratory profiles and comparison with primary Sjögren's syndrome by Menelaos N. Manoussakis; Chryssoula Georgopoulou; Elias Zintzaras; Marilyn Spyropoulou; Aikaterini Stavropoulou; Fotini N. Skopouli; Haralampos M. Moutsopoulos is a Medicine article available to read on EtoBox.

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## Abstract ## Objective. To address the clinical, serologic, pathologic, and immunogenetic features of sicca syndrome that occurs in systemic lupus erythematosus (SLE), as well as its similarities to, and differences from, sicca syndrome that occurs in primary Sjögren's syndrome (SS). ## Methods. A cohort of 283 consecutive unselected SLE patients was evaluated for the presence of associated SS using the American–European classification criteria. Clinical and laboratory parameters in SLE patients with SS (SLE–SS) were compared with those in SLE patients without SS (SLE–no SS) and with a group of 86 unselected patients with primary SS. ## Results. SS was identified in 26 SLE patients (9.2%); the SS preceded the development of lupus in 18 of them (69.2%). Compared with the SLE–no SS group, patients with SLE–SS were significantly older, had a higher frequency of Raynaud's phenomenon, anti‐Ro/SSA, anti‐La/SSB, and rheumatoid factor, but had a significantly lower frequency of renal involvement, lymphadenopathy, and thrombocytopenia. Compared with the primary SS group, SLE–SS patients displayed a clinically similar sicca syndrome, but were significantly younger and had an increased freq

Who reads Sjögren's syndrome associated with systemic lupus erythematosus: Clinical and laboratory profiles and comparison with primary Sjögren's syndrome?

Author

Menelaos N. Manoussakis; Chryssoula Georgopoulou; Elias Zintzaras; Marilyn Spyropoulou; Aikaterini Stavropoulou; Fotini N. Skopouli; Haralampos M. Moutsopoulos

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0004-3591)

Published

2004

Language

EN

Field

Medicine (Health Sciences)