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This study compares the ligand binding specificity and tissue distribution of two estrogen receptor subtypes, ERa and ERb, in rats. It finds that both receptors exhibit different affinities for various estrogenic compounds and have distinct expression patterns across tissues, which may contribute to their selective actions in different biological contexts. The research highlights the importance of understanding these differences to elucidate the roles of estrogens in growth and differentiation of target tis

Author

Yuling Xie

Language

EN