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Valve‐in‐Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement for Failed Surgical Aortic Bioprostheses: A Systematic Review and Meta‐Analysis by Matthias Raschpichler; Suzanne de Waha; David Holzhey; Guido Schwarzer; Nir Flint; Danon Kaewkes; Paul T. Bräuchle; Danny Dvir; Raj Makkar; Gorav Ailawadi; Mohamed Abdel‐Wahab; Holger Thiele; Michael A. Borger is a Medicine article available to read on EtoBox.

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## Background In the absence of randomized controlled trials, reports from nonrandomized studies comparing valve‐in‐valve implantation (ViV) to redo surgical aortic valve replacement (rAVR) have shown inconsistent results. ## Methods and Results PubMed/MEDLINE, Google Scholar, and CENTRAL (Cochrane Central Register of Controlled Trials) were searched through December 2021. Meta‐Analysis of Observational Studies in Epidemiology guidelines were followed. The protocol was registered at the International Prospective Register of Systematic Reviews. Random effects models were applied. The primary outcomes of interest were short‐term and midterm mortality. Secondary outcomes included stroke, myocardial infarction, acute renal failure, and permanent pacemaker implantation, as well as prosthetic aortic valve regurgitation, mean transvalvular gradient, and severe prosthesis‐patient mismatch. Of 8881 patients included in 15 studies, 4458 (50.2%) underwent ViV and 4423 (49.8%) rAVR. Short‐term mortality was 2.8% in patients undergoing ViV compared with 5.0% in patients undergoing rAVR (risk ratio [RR] 0.55 [95% CI, 0.34–0.91], __P__=0.02). Midterm mortality did not differ in patients undergoin

Who reads Valve‐in‐Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement for Failed Surgical Aortic Bioprostheses: A Systematic Review and Meta‐Analysis?

Author

Matthias Raschpichler; Suzanne de Waha; David Holzhey; Guido Schwarzer; Nir Flint; Danon Kaewkes; Paul T. Bräuchle; Danny Dvir; Raj Makkar; Gorav Ailawadi; Mohamed Abdel‐Wahab; Holger Thiele; Michael A. Borger

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2022

Language

EN

Field

Medicine (Health Sciences)