Can I read Biomarkers for Early Diagnosis of Alzheimer's Disease on EtoBox?

Biomarkers for Early Diagnosis of Alzheimer's Disease by Daniela Galimberti; E Scarpini is a nonfiction available to read on EtoBox.

What is Biomarkers for Early Diagnosis of Alzheimer's Disease about?

Alzheimer's disease (AD) is characterized by the deposition into the brain of amyloid peptide, which originates a cascade of inflammatory events leading eventually to neuronal death. These pathological events likely occur several years before the clinical manifestation of the disease, implying that potential therapeutical interventions are currently started too late to give beneficial results. Recently, growing attention has been paid to the Mild Cognitive Impairment (MCI), considered the prodromal phase of AD, as 80 per cent of subjects with MCI have been shown to develop AD within 5 years. Several studies aimed to identify biological markers to differentiate between normal aging and incipient AD have been carried out, including cerebrospinal fluid (CSF) analysis and neuroimaging. In particular, the evaluation of CSF Amyloid beta (1-42) levels, together with tau and phospotau, are of help for recognizing early AD. Besides, a number of additional molecules are altered in CSF. Other early modifications have been observed in peripheral cells, such as fibroblasts and leukocytes, as well as in serum from patients. Biomarkers for AD represent important tools supporting the clinical diag

Who reads Biomarkers for Early Diagnosis of Alzheimer's Disease?

Author

Daniela Galimberti; E Scarpini

Publisher

Nova Biomedical Books

Published

2008

Language

EN

ISBN

9781604569919

Category

nonfiction

Subjects

Medical, Health & Fitness, Science