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This document evaluates the NanoString Technologies nCounter platform for multiplexed gene expression analysis of clinical samples, particularly focusing on its robustness and sensitivity when analyzing low-quality RNA from formalin-fixed paraffin-embedded (FFPE) tissues. The study demonstrates that the nCounter platform offers advantages in sensitivity, reproducibility, and technical robustness, making it suitable for clinical applications. Various technical variables were assessed, including RNA quality,

Author

Ferdinando de Paula

Language

EN